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Ferroptosis and cancer: Mitochondria meet the Iron Maiden cell death

It transports essential nutrients and water elements back to the root

Eventually, this leads to the production of lipid aldehydes, which initiate ROS-mediated peroxidation and subsequently trigger apoptosis (39, 40)

3.3 Anti-inflammatory cytokine Activated astrocytes modulate neuroinflammatory responses and promote tissue repair through the release of various anti-inflammatory substances

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Inhibition of iNOS reduced HIF-1 accumulation and worsened epithelial damage, emphasizing NOs protective role via this pathway (111113)