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FIGURE 2 All the PDEs are composed of three functional regions: a C-terminal, an N-terminal, and a conserved catalytic region

Alan Gaby, a president of the American Holistic Medical Association

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These disruptions in fuel homeostasis are not clearly related to their primary action of fluid management, raising concerns for patients with metabolic syndrome, in which high blood pressure coexists with obesity, insulin resistance, glucose intolerance and dyslipidemia