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Renal, Liver, and Heart Histology The same scoring system as in the previous studies [12,13,14,15,16,20,22,23,24] was used to grade renal (i.e., the degeneration of Bowmans space and glomeruli, degeneration of the proximal and distal tubules, vascular congestion, and interstitial edema), liver (i.e., vacuolization of hepatocytes and pyknotic hepatocyte nuclei, activation of Kupffer cells, and enlargement of sinusoids) and heart (i.e., dilatation and congestion of blood vessels within the myocardium and coronary arteries) histology

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J Mol Med (Berl) 95:323333 Hsieh MJ, Lee CH, Chueh HY, Chang GJ, Huang HY, Lin Y et al (2020) Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway

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Month 5-6 (12.5-15 mg): Higher doses produce the strongest appetite suppression but also carry the highest risk of side effects

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