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Description
3 Bromopyruvate sensitizes human breast cancer cells to TRAIL induced apoptosis via the phosphorylated AMPK mediated upregulation of DR5

Hicks S, Labinskyy N, Piteo B et al (2013) Type II diabetes increases mitochondrial DNA mutations in the left ventricle of the Goto-Kakizaki diabetic rat

Methods Chemicals The following chemicals were purchased for cultivation and extraction of bacterial cultures: MeOH and EtOH (Mallinckrodt Baker B.V., Deventer, Holland), pepton tryptone, yeast extract (Oxoid Hamphsire, England), NaCl (Carl Roth, Karlsruhe, Germany) and D-(+)-glucose monohydrate (Fluka, Sigma Aldrich, Steinheim, Germany)

10.4049/jimmunol.1100613 7 Bayet-RobertM.MorvanD

[1] [2] The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment

However, for the treatment of fatigue in fibromyalgia, the clinical study showed that there was no significant difference in any effectiveness outcome and failed to treat the fatigue associated with fibromyalgia [46,49,58]
