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Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al

Alveolar epithelial and endothelial cell apoptosis in emphysema: What we know and what we need to know

It is integral to the livers detoxification of environmental toxins, heavy metals, and certain medications

doi: 10.1007/s10103-016-1946-3

Annexin V-FITC and propidium iodide (PI) were purchased from Genview (Gen-view, scientific Inc., USA), while calcein-AM and cell counting kit-8 (CCK-8) were provided by Bestbio (Shanghai, China)

The mechanism differentiates it from general GH-axis stimulation