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[3] Research suggests these findings might indicate selective adipose tissue activity that mechanistically diverges from that of intact hGH, which is believed to produce insulin resistance in preclinical models at comparable biological concentrations

As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Tilg et al., 2020)

Pre-existing conditions such as diabetes require close monitoring throughout treatment

Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates selective actions relative to 3,5,3'-triiodo-L-thyronine

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