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Taking the anti-histamine drugs cetirizine hydrochloride and chlorpheniramine maleate combined with l-carnitine showed a hepatoprotective effect in animal models, via a reduction in oxidative stress and an improvement in liver function due to the elevation of serum albumin levels and a reduction in serum alkaline phosphatase (ALP), aspartate transferase (AST), and alanine transferase (ALT) levels

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For MSU crystals, binding of the catalytic subunits C1r and C1s were mainly increased in their proteolytically cleaved/active form

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