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BPC-157 appears to work primarily through nitric oxide pathways and growth factor modulation studies have shown it influences VEGF expression, which plays a role in new blood vessel formation, and it appears to interact with the dopaminergic and serotonergic systems in neurological research models

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This correlation is believed to be due to widespread autoimmune processes, such as destruction of thyroid follicular cells and epidermal melanocytes by cytotoxic CD8 T cells and increased levels of antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TG) antibodies in patients with vitiligo

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