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To enhance the quality of evidence, larger sample sizes and multi-center, double-blind RCTs should be conducted

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Third, a major emerging concept is that overall immune health, including immune history and lifestyle, plays a substantial role in shaping potential immune responsiveness to future interventions

This therapeutic effect could be related to different vitamin D mechanisms including the known effect on mood [110], pain [87,88] and sleep

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[49] Gelatin is also used as a saturating agent in immunoassays, and as a coat
