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Treatment rationale and study design for a randomized, double-blind, placebo-controlled phase II study evaluating onartuzumab (MetMAb) in combination with bevacizumab plus mFOLFOX-6 in patients with previously untreated metastatic colorectal cancer

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L-theanine supplementation improved tight junction (TJ) barrier integrity by enhancing the expression of ZO-1, occluding, and claudin-3 in the intestine [46]

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