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The overexpression of complement components C3, C5, and C9 has been observed in patients with OSAHS (78), indicating an activation of the complement system (78, 79)

thus, the levels of pyruvate carboxylase can greatly affect the sensitivity of tumor cells to inhibition of glutamine metabolism 111

The increased presence of free radicals is a contributing factor in the onset of aging, cancer, cardiovascular diseases, dementia, and many chronic-degenerative illnesses

J Biol Rhythms 1997

Exploring natural products as radioprotective agents for cancer therapy: mechanisms, challenges, and opportunities