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Bioavailability and administration routes of traditional Chinese medicine for intestinal barrier targeting in NAFLD Overview of TCM bioavailability in NAFLD therapy Bioavailability, defined as the fraction of an administered drug that reaches the systemic circulation and exerts biological effects, is a pivotal determinant of the therapeutic efficacy of TCM in NAFLD

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5.4 Western diet The dietary structure of western diet pattern represented by western developed countries is characterized by high energy food intake, high protein, saturated fat, refined cereals, sugar, alcohol and salt, and low intake of omega-3 fatty acids, fruits and vegetables, thus has the diet pattern of three highs of high calories, high fat and high protein

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