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Baseline reductions in structural connectivity also predict progression to poor cognitive outcomes at 3-year follow-up 141 and in PD patients with MCI they predict progression to dementia within 5 years 144 , with interhemispheric frontal and parietal connections being most implicated in cognitive impairment 141,144,145

here, we focus on therapeutic strategies that aim to activate autophagy to ameliorate dysproteostasis

For example, irreversible electroporation may cause prostate cancer patients loosing up to 41% potency post-treatment [226]

Discovery of novel, drug-like ferroptosis inhibitors with in vivo efficacy

Research suggests that optimizing growth hormone levels through Sermorelin may support various aspects of healthy aging including body composition, energy, sleep, skin health, bone density, and metabolic function

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