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The FDA has issued safety communications regarding compounded GLP-1 receptor agonists, including tirzepatide and semaglutide, warning about adverse events from bacterial contamination, incorrect dosing, and use of improper ingredients

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This review integrates current mechanistic insights with orthopaedic relevance, emphasizing safety, efficacy, and future directions for responsible integration into musculoskeletal care

That removal took effect seven days later, on April 22

171 The development of small molecule GLP-1RAs aims to overcome some of the limitations of traditional protein or peptide-based GLP-1RAs, such as the need for injection