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By crossing a mouse model of DS (the Tc1 mouse) that does not have an additional copy of APP to a transgenic mouse overexpressing APP with AD-causing mutations (J20 mouse), the additional copy of Hsa21, independent of an extra copy of APP , exacerbated A aggregation and deposition, enhanced APP transgene-associated mortality, altered behavior, and reduced cognitive performance in double-mutant progeny that model DSAD (477)

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Faster recovery after exercise, It may help reduce muscle damage and inflammation, potentially leading to quicker recovery times between workouts

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Gertrude Elion, who earned a masters degree in chemistry from New York University in 1941, worked as a lab assistant for George Hitchings

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doi:10.1186/s12944-018-0876-4 Sabbatinelli J, Orlando P, Galeazzi R, et al

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Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau

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FLHS is often connected with a suboptimal energy-protein ratio

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