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Epithalon is a synthetic peptide studied extensively for longevity and cellular health applications

In ophthalmology, the role of GCH1 could be crucial for maintaining retinal integrity and eliminating specific eye disorders, such as AMD and other retinal degenerative diseases (59)

The results of pharmacokinetic parameters presented in Table 9, indicate that almost same C max values of diosgenin, charantin, and hydroxychalcone, 0.57 and 0.61 g/ml, 0.71 and 1.06 g/ml, and 5.42 and 5.35 g/ml, respectively, for i.v

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Furthermore, VMAT2-knockout mice are sensitive to the neurotoxic drug methamphetamine [46, 47], which promotes DA redistribution from synaptic storage vesicles into the cytosol [48, 49]

This accumulation of lipid peroxides is lethal to the cell and is a key feature that differentiates ferroptosis from other cell death pathways