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Left gel shows very little GST-fusion protein in the flow-through and a lot in the elution indicating that sufficient glutathione agarose resin was used in this purification

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However, we found a significant negative correlation between GSH levels and the severity of negative symptoms (SANS total score and negative symptom subscore on BPRS) in patients

It is exceptionally high in cysteine

It has been implicated in the regulation of enzyme activities, in DNA synthesis, in maintaining the viability of chloroplasts and mitochondria, in the protection of nitrogenase from inhibition by oxygen, and in the regulation of gene expression.* Glutathione levels decrease naturally with age, as well as with certain stressors, including exercise, smoking, and pollution