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3.2 Transcriptome analysis 3.2.1 In healthy animals, vitamin B12 causes only minor changes in the hippocampal transcriptome The contrast between Sham-infected + B12 and Sham-infected + placebo disclosed 17 genes up-regulated and 21 genes down-regulated in healthy animals treated with the vitamin ( Figure 2A )

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Patients with pacemakers who also take digoxin, a cardiac glycoside used for certain arrhythmias, should inform their prescribing physician because rapid weight loss can affect drug levels in the bloodstream