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The SLC16A1 gene, that encodes MCT1, is expressed in multiple tissues
Further testing of antioxidative agents on these models would help to evaluate the safety and effectiveness of such treatment
10.1038/ng.186 181
Vukojevi J, Vrdoljak B, Malekinui D, Siroglavi M, Milavi M, Kolenc D, et al
Considering the relatively high concentrations of NADH and NAD + in the mitochondrial matrix, most of which exist in their free forms [54], it is questionable whether complex I serves as the primary source of ROS generation within mitochondria under physiological conditions
10.1016/j.cmet.2018.05.011 Cell Metab
