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The extracellular matrix components are degraded by macrophage-derived matrix metalloproteinases, (201-203) elastases, and cathepsins (Figure 5) (204)

Fatty change was reported in the X-zone (basophilic cells that surround the medulla around 10 days of age, then gradually disappear as mice mature) of the adrenal glands of 8 of 10 high-dose female mice

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During opiate withdrawal, the absence of opioid receptor activation unmasks this heightened sensitivity
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