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A meta-analysis of randomized controlled trials (RCTs) and observational studies investigated the dose-response relationship between vitamin B12 intake and serum or plasma vitamin B12 concentrations

1 Unlike other vitamins, vitamin B12 is not produced by the body and must be obtained through food intake and supplementation

USA 72 , 10031006 (1975)

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Further analysis revealed an additional nausea and vomiting association in the GIPR locus specifically within the tirzepatide-treated population

This is usually less than 1.5 milliliters (mL), but up to 3 mL may be administered into the abdomen