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Inherited Complement Regulatory Protein Deficiency Predisposes to Human Disease in Acute Injury and Chronic Inflammatory Statesthe Examples of Vascular Damage in Atypical Hemolytic Uremic Syndrome and Debris Accumulation in Age-Related Macular Degeneration

Simultaneously, the opening of the mitochondrial permeability transition pore induces mitochondrial swelling and rupture, releasing apoptotic factors and ultimately leading to cell death [34, 35]

doi: 10.1055/s-2006-957816 136 DengXZhaoJQuLDuanZFuRZhuCet al

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These findings suggest exploiting cellular metabolic plasticity to modulate T-cell metabolism and antitumor immune responses through glutamine blockade