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The most abundant CYP isoform in the human liver and intestines is cytochrome P450 3A4 (CYP3A4), which catalyzes the metabolism of about half of all marketed drugs in the US (156)

Ammendola A, Tata MR, Aurilio C, Ciccone G, Gemini D, Ammendola E, et al

Results in animal studies "In rodent experiments led by Dr

[DOI] [PubMed] [Google Scholar] Hopf FW, Bowers MS, Chang SJ, et al

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After 18 days (D24) of L-carnitine intervention, the four groups of mice were sacrificed using 4% isoflurane, then blood and tissue samples were collected and evaluated