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This timing aligns MOTS-c's AMPK activation with the metabolic demands of training

doi: 10.3389/fphar.2017.00326 131 IzawaMTanakaNMurakamiTAnnoTTeranishiYTakamatsuKet al

452 These STAT1 heterodimers bind to IRF1 to form a complex, 473 which then translocates to the nucleus and binds to the IRF1 response element (IRE), modulating the transcription of PD-L1 genes and upregulating PD-L1 expression

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