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At the presynaptic level, misfolded syn aggregates accumulate in the terminal, binding to membranes and altering curvature [195]

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Micronutrient deficiencies prevail in cases of Polycystic Ovary Syndrome among women and might be the cause of the progression of the disease [21]

177 Peripheral inflammation is associated with the activation of immune cells, including T cells, macrophages, and monocytes, which can breach the BBB due to their increased permeability in this disease state

10.1038/s41419-020-2618-6 8