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Clinical review 66

Ranke MB, Savage MO, Chatelain PG, Preece MA, Rosenfeld RG, Blum WF, Wilton P: Insulin-like growth factor I improves height in growth hormone insensitivity: two years results

Palefsky J

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There is a need for new, safe, and effective therapeutics with extensive safety and efficacy data that can be developed for use in humans within the next few years

In addition, artesunate inhibits PF by regulating the expression of the profibrotic proteins, type IV collagen, TIMP-1/2, MMP-2/9, TGF-1, Smad3, HSP47, -SMA, and type I collagen (Wang et al., 2016