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Of note, gastrointestinal (GI) disorders such as gallstones and gastroesophageal reflux disease (GERD) have been identified as mostly non-metabolic complications of obesity and are also listed among possible adverse events (AE) of incretin-based AOM

Gastroenterology 142 , 947956 (2012)

& Nedergaard, M

Importantly, the TME does not only surround the tumor cells, it actively contributes to tumor development and progression (47), drug resistance (48), and metastasis (49)

doi: 10.1179/147683008X301360 22 AnhNKThuNQTienNTNLongNPNguyenHT

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