bpc-157 systematic review 544 published articles on BPC-157. 36 met inclusion criteria for a 2025 review. 35 were animal studies. One was clinical. Twelve patients. Seven reported pain relief. No control group. That is The Hidden Risks of BPC‑157:

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Injection of local anesthetic deep to this sheath (but outside the epineurium of the tibial or common peroneal nerves) has been shown to spread a considerable distance proximally and distally, and result in a rapid onset, dense block

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