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and the design of the container closure system affects the dosing performance of the drug product [24]

ABHD5 ligands that release ABHD5 from PLIN1 or PLIN5 independent of PKA activation, led to the discovery of long-chain acyl-CoA (LC-CoA) as an endogenous allosteric regulator of ABHD5 that promotes the interaction with PLIN1/5 (48)

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Another known cause of cobalamin deficiency is Diphyllobothrium latum (D

Studies examine how activating all three pathways simultaneously influences metabolic outcomes

Some patients are trained to self-inject after the first few doses at the clinic