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Its effect is specific to adipose tissue metabolism
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But their actual effectiveness often remains debated

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In fact, the chemical structure of alkali is similar to choline, similar to amino acids
In this respect, an interesting study conducted on immortalized human microglia cells (CVCL_5G94) highlighted how ATRAs can increase the heat shock protein 90 (Hsp90) expression on the surface of these cells, causing an increase in the amount of endocytosed and consequently eliminated tau protein (25)