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PCSK9 Modulates Macrophage Polarization-Mediated Ventricular Remodeling after Myocardial Infarction

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Furthermore, a mechanistic link between ER stress and autophagy suggests that ER stress and unfolded protein response pathways can induce the expression of autophagy-related protein by activating ER stress sensors 16

impaired fatty acid -oxidation metabolism and impaired branched-chain amino acid metabolism can lead to the accumulation of large amounts of acyl CoA

3.2.2 Mitochondrial structure The improvement of cognitive function and ambulatory activity following acetylcarnitine supplementation [82], was related to restored mitochondrial cristae [83] and reduction of oxidized RNA, likely mitochondrial [84], in hypocampus neurons