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Corticosteroids Corticosteroids provide rapid symptom relief but carry substantial risks: immunosuppression, impaired wound healing, tendon weakening with increased rupture risk, hyperglycemia, and osteoporosis with chronic use

It is well known that increase of intracellular ROS, RNS and Ca 2+ has main roles in etiology of pain processes (Kallenborn-Gerhardt et al., 2012

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While BCVA is a well-established endpoint in exudative AMD, its sensitivity and reliability in drusen-predominant disease are limited

However, the absorption of Se also depends on the content of protein, fat, heavy metals, and other compounds in the diet, and food preparation practices (55), and from the average diet, the Se absorption is approximately 7080% (45, 57)

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