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The Fenton reaction, in which iron catalyzes the production of reactive oxygen species (ROS) that target polyunsaturated fatty acids (PUFAs) in cell membranes, can cause ferroptosis in endothelial cells

Although one of these sites is located in the 5 promoter region and the other site in the 3 flanking region, both sites are functional, as they have both been shown to bind the PU.1 nuclear factor in gel mobility shift assays, and both mediate transcription, as assessed by reporter gene assays

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[PMC free article] [PubMed] [Google Scholar] 339.Feng M., Smith D.E., Normolle D.P., Knol J.A., Pan C.C., Ben-Josef E., Lu Z., Feng M.R., Chen J., Ensminger W., et al

Extracting the Full Potential of Single-Walled Carbon Nanotubes as Durable Supercapacitor Electrodes Operable at 4V with High Power and Energy Density