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In this text-mining study, the AD-pathway_score (ranging from 1 to 5) reflects the strength of the relevance of a given pathway to AD, based on a curated review of the specific pathway-associated literature (lower scores indicate stronger associations)

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

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It has been reported that this microbiome has a diverse role as it maintains a dynamic and regulated interaction with the immune system, which, upon shifting microbiome patterns, plays a key role in rejection in recipients of organ transplants by dysregulating the immune system