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Jul 27 2021;13(7):763-773

In fact, many studies demonstrated that TMAO-induced NF-B activation is a significant downstream process that upregulates monocyte adhesion through upregulation of cellular adhesion molecules such as VCAM-1, but also intercellular adhesion molecule 1 (ICAM-1) and E-selectin, and enhances endothelial dysfunction [14,15]

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a , Volcano plot showing protein expression changes in knee joints following two doses of K9 LNP (mCas9 + sgTOM) treatment, as identified by LC-MS/MS