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Neuroinflammation Chronic neuroinflammation (activation of microglia and release of cytokines) contributes to PD progression [69]

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The Full Answer to What Is MOTS-c at the Molecular Level MOTS-c stands for mitochondrial open reading frame of the 12S rRNA type-c. That mouthful describes exactly what it is: a small protein encoded by a short open reading frame inside the mitochondrial 12S ribosomal RNA gene

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DNA may be damaged, as a result of oxidative stress, from the reactions between hydroxyl radicals and all of the components of the DNA molecule, including the pyrimidine and purine bases and deoxyribose backbone