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Description
Macrophage polarization in health and disease

Its main product, ADPR, can either be metabolized by the CD203a/CD73 exoenzymatic tandem into ADO (40), which binds to purinergic type 1 (P1) receptors (particularly A2A and A2B), or facilitate Ca2+ influx through TRPM2 channels (45)

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Nation Research Council (US)

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