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A few practical points carry more weight than the short side-effect list: No use in pregnancy or breastfeeding

There are practical reasons too: B can be unstable if mixed with certain other vitamins in solution, and dosing schedules for B deficiency (pernicious anemia, for instance) may differ

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Jonathan Hommel for guidance in the original study design, and Dr

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doi: 10.3389/fimmu.2018.02134 Received 09 June 2018 Accepted 29 August 2018 Published 20 September 2018 Volume 9 - 2018 Edited by Fabio Malavasi, Universit degli Studi di Torino, Italy Reviewed by Benjamin Bonavida, University of California, Los Angeles, United States