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Daniel Uba, MD Published May 6, 2026 19 min read PCOS management hasn't fundamentally changed in decades

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Common risk factors include: A plant-based or vegan diet Digestive conditions like Crohns disease or IBS Long-term use of metformin or acid-reducing medications Aging (B12 absorption naturally declines over time) Chronic stress and poor sleep Why oral B12 supplements often fall short Oral supplements are widely available but their biggest limitation is B12 absorption
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doi: 10.1016/j.imbio.2020.151999

demonstrated that Kamikihito reduced anxiety levels and enhanced consummatory hedonic responses in C57BL/6J mice
