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Mechanisms of Formaldehyde Sensing The various pathways for formaldehyde detoxification operate under the control of formaldehyde-responsive transcriptional factors but the biochemical mechanisms for formaldehyde sensing remain poorly understood

The first step in GSH synthesis is catalyzed by l-glutamate l-cysteine -ligase (GCL), resulting in the formation of -glutamyl-cysteine

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Plant Mol Biol 80(6):587608

Collectively, these findings demonstrate that NAMPT-mediated control of NAD + is fundamental for balancing monocyte energy metabolism with their functional immune roles

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