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In ovarian protection, melatonin promotes the phosphorylation of malic enzyme 1 (Mel), modulates NADPH levels, and enhances the activity of antioxidant enzymesincluding SOD, CAT, GPX and glutathione reductase (GR)along with GSH content., collectively restoring mitochondrial function and lessening granulosa cell apoptosis (152)

Leclerc, H

Decrease of NADPH (measured at the wavelength of 340 nm) is proportional to GPx activity

10.3892/ijo.2021.5173 100 TanH.LuoW.WeiL.ChenB.LiW.XiaoL.et al (2016)

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