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Nevertheless, the mechanism by which topical GSSG effectively whitens skin is not clear, and the relevance of GSH reduced from topical GSSG in the skin is no more than speculation

Record retention and archival All the study documents including participants source data and documents will be archived by the study sites after the completion of the study, until the time the sponsor informs in writing to the study sites that they no longer need to maintain the study documents

Unsurprisingly, scientists are interested in interventions that can target and increase glutathione levels, including whether glutathione supplements would be effective

This is a conflict of interest that does not invalidate the research but requires independent confirmation, which has been limited

Further investigation is necessary to fully characterize the complex biological mechanisms through which glutathione influences cellular health and physiological function