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Using a human proteome microarray, the authors showed PTMA as a novel OSF-specific autoantigen, linked with fibroblast proliferation and ECM regulation in a TGF-1-induced cell fibrosis model

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CNS-directed treatments include intrathecal chemotherapy, CNS-directed systemic chemotherapy, and cranial radiation

The connection between glycolysis and PD involves the enzyme phosphoglycerate kinase 1 (PGK1), the first ATP-producing enzyme in the glycolytic pathway, encoded by the PGK1 gene

M.KaznessisY

TNF- expression was lower in the brain of KD-R-fed mice than in the brain of SD-UR-fed mice, whereas TNF- expression was even lower in the KD-R + DON-treated mice, suggesting a minimum amount of tumour load and reduced inflammation compared to the other two groups (Fig