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After ingestion, MNPs can cross the gastrointestinal barrier, with smaller particles more readily entering systemic circulation via the portal vein [46]

Differentially expressed genes (DEGs) between vehicle-treated and drug-treated groups were identified using the Bioconductor/R package DESeq2 69 , with an adjusted p value (false discovery rate) of 10% or less being considered differentially expressed

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doi: 10.1007/s12035-019-01712-8 21 DeanO.GiorlandoF.BerkM

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The direct effects of climate change can also alter the phenology and spread of pathogens