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In summary, studies of association between genetic variants in the DNA repair system and clinical results show that these variants can be potential biomarkers for outcomes in the cisplatin-based therapies (Table 1)

zinc acetate) with subsequent acidification and reaction with N, N-dimethyl-p-phenylenediamine (DMPD) to form methylene blue that is measured using a spectrophotometer or plate reader at 670 nm

Salyer SW

Bioorg Med Chem 19:951960 Samsonowicz M, Regulska E (2017) Spectroscopic study of molecular structure, antioxidant activity and biological effects of metal hydroxyflavonol complexes

Previous studies have demonstrated that the interactions between TIICs and prostate cancer cells can serve as therapeutic targets, with experimental evidence supporting these relationships (260, 261)

Collagen also has the ability to alter the gut microbiota while increasing the production of short-chain fatty acids (SCFAs) and acting as a source of prebiotics