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2019;31(27) doi: 10.1002/adma.201901103

Some patients experience mild injection site reactions (redness, slight swelling) which typically resolve quickly

Often paired with D3 at 100-200 mcg daily

Modulation of the Inflammatory Microenvironment : MSCs and NK cells downregulate TNF-, IL-1, and S100A9pro-inflammatory cytokines implicated in ineffective hematopoiesis and stem cell exhaustion

Any history of tumors or cancer requires serious medical caution

Exogenous sources include radiation, UV light, x-rays, gamma rays, chemicals that react to form peroxides, ozone and singlet oxygen, chemicals that promote superoxide formation, quinones, nitroaromatics, bipyrimidiulium herbicides, chemicals that are metabolized to radicals e.g., polyhalogenated alkanes, phenols, aminophenols etc