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The aim of this critical state-of-the-art review is to summarize the potential biochemical, pathophysiological and diagnostic spectrum of CRP, Moreover, the current CRP diagnostic assays and reasons of potential misdiagnoses and possible false test results are thoroughly presented

For (d-f), data are presented as mean +/ SD, n = 3 independent replicates

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Several studies concerning the prognostic role of serum CK in other cancers, including hepatocellular cancer [15], esophageal cancer [12], and gastric cancer [13], had indicated low serum CK concentration was a predictor for poor OS and recurrencefree survival (RFS) in male patients rather than female patients

doi: 10.1016/j.freeradbiomed.2021.05.032 96

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