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Despite the large number of clinical and preclinical trials worldwide, no significant positive success in the use of anti-HGF/c-Met treatments on cancers of the digestive system has been achieved

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Furthermore, estrogen has been found to increase vitamin D receptor (VDR) gene and protein expression as well as 1,25(OH) 2 D 3 activity in the colon, which leads to increased intestinal calcium absorption [101, 102]

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For example, one study revealed that 7 days of therapy in rats led to a significant increase in serotonin synthesis in their brains

Another area that is pertinent to the concept of precision nutrition is epigenetics. This refers to the chemical modification of DNA and associated histones that control, among other processes, whether individual genes are expressed