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So I tried to dig into why this could potentially be the case
doi: 10.1113/expphysiol.2009.048330 80 WittwerEDLiuZWarnerNDSchroederDRNadeauAMAllenARet al
These substances are often substances produced by the body (metabolites) that cannot be removed properly due to the impaired function of the kidneys
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[DOI] [PubMed] [Google Scholar] 7.Henrotin Y., Kurz B., Aigner T

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