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Bao Z, Liu Y, Chen B, Miao Z, Tu Y, Li C, et al

Research centered on colorectal cancer (CRC) revealed that CAFs with Ras-related protein Rab-31 (RAB31) controlled the release of HGF, thus promoting the movement of CRC cells [48]

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In the CNS, AIM2 expression has been detected in microglia and astrocytes, and AIM2 activation has been linked to neuroinflammatory responses and cognitive deficits in experimental models of neurodegeneration and traumatic brain injury

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The activation of the NLRP3 inflammasome further exacerbates inflammatory injury (Ning et al., 2020)